BDBM50001683 13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid::7-Benzyl-10-{[3-(4-hydroxy-phenyl)-pyrrolidine-2-carbonyl]-amino}-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL294616::DPDPE
SMILES CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N[C@H]1C(O)=O
InChI Key InChIKey=MCMMCRYPQBNCPH-DVKRWUGUSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 49 hits for monomerid = 50001683
Affinity DataKi: 3nMAssay Description:Binding affinity against opioid receptor by displacing radioligand [3H]DPDPEMore data for this Ligand-Target Pair
Affinity DataKi: 82nMAssay Description:Binding affinity towards opioid receptor mu 1More data for this Ligand-Target Pair
Affinity DataKi: 460nMAssay Description:Binding affinity of the compound towards opioid receptor mu 2More data for this Ligand-Target Pair
Affinity DataKi: 504nMAssay Description:Displacement of [3H]DAMGO from human MOP receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 504nMAssay Description:Displacement of [3H]DAMGO from human recombinant Opioid receptor mu 1 on CHO cell membranes.More data for this Ligand-Target Pair
Affinity DataKi: 610nMAssay Description:Displacement of [3H]DPDPE from rat mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 610nMAssay Description:Displacement of [3H]DAMGO from rat mu opioid receptor expressed in mouse HN9.10 cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 810nMAssay Description:Binding affinity against opioid receptor mu in guinea pig brain homogenates, using [3H]DAMGO as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 810nMAssay Description:Compound was tested for the inhibition of [3H]- [D-Ala2, N-MePhe4, Gly5-ol]-enkephalin (DAMGO) binding to mOpioid receptor mu 1 in guinea pig brain h...More data for this Ligand-Target Pair
Affinity DataKi: 873nMAssay Description:Inhibition of [3H]-DAGO binding to rat brain membrane Opioid receptor mu 1More data for this Ligand-Target Pair
Affinity DataKi: 873nMAssay Description:Inhibition of [3H]DAGO binding to mu 1 opioid receptor in rat brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 943nMAssay Description:Tested for binding affinity against mu opioid receptor fby displacing [3H]- DAMGO radioligand from rat brain membrane preparationsMore data for this Ligand-Target Pair
Affinity DataKi: 2.02E+3nMAssay Description:In Vitro evaluation for the binding affinity in homogenates of rat brain at opioid receptor mu by displacing [3H]- DAMGOMore data for this Ligand-Target Pair
Affinity DataKi: 2.12E+3nMAssay Description:Displacement of [3H]DAMGO from Sprague-Dawley rat mu opioid receptor by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:In vitro potency was measured against human Opioid receptor mu 1More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of binding of [3H]diprenorphine to cloned human Opioid receptor mu 1 expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 609nMAssay Description:Compound was evaluated for its ability to displace [3H]- CTOP (opioid receptor mu selective ligand)More data for this Ligand-Target Pair
Affinity DataKd: 577nMAssay Description:Binding affinity against Mu opioid receptor using [35S]GTP-gamma-S, binding assay in guinea pig caudate membranes in unblocked conditionMore data for this Ligand-Target Pair
Affinity DataKd: 577nMAssay Description:Binding affinity against Mu opioid receptor using [35S]GTP-gamma-S, binding assay in guinea pig caudate membranes in unblocked conditionMore data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+3nMAssay Description:Compound is tested in vitro in guinea pig ileum (GPI) assay mediated by Opioid receptor mu 1More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Opioid receptor mu 1 binding affinity in rat brain membrane preparations by the displacement of [3H]- DAGOMore data for this Ligand-Target Pair
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibitory activity measured against Opioid receptor mu 1 using guinea pig ileum assay (GPI).More data for this Ligand-Target Pair
Affinity DataIC50: 619nMAssay Description:Inhibitory activity measured against [3H]CTOP (Opioid receptor mu 1) in rat brain using radioreceptor binding assays.More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of electrically evoked contraction of guinea pig ileum (myenteric plexus:longitudinal muscle preparation) by antagonist action at mu 1 opi...More data for this Ligand-Target Pair
Affinity DataIC50: 385nMAssay Description:The ability to displace [3H]naloxone from the Opioid receptor mu 1 isolated from rat brain membrane.More data for this Ligand-Target Pair
Affinity DataIC50: 609nMAssay Description:Ability to displace [3H]CTOP from Opioid receptor mu 1 in rat brain membranes, was determined from radioreceptor assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.30E+3nMAssay Description:Tested for agonist activity against mu opioid receptor in guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 7.30E+3nMAssay Description:Binding affinity towards Opioid receptor mu 1 was determined in guinea pig wholebrain using [3H]CTOP radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory concentration was determined against Opioid receptor mu 1 using [3H]- DAMGO radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Tested for inhibitory concentration against [3H]DAMGO binding at sites of mu-opioid receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 7.30E+3nMAssay Description:The opioid activity against the mu-receptor in the isolated guinea pig ileum(GPI)More data for this Ligand-Target Pair
Affinity DataIC50: 7.30E+3nMAssay Description:Agonistic activity for Opioid receptor mu 1 as inhibitory activity towards electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 1.76E+3nMAssay Description:Tested for the binding affinity against the Mu opioid receptor in guinea pig brain using [3H]-DAMGOMore data for this Ligand-Target Pair
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibitory activity of the electrically induced guinea pig ileum longitudal muscle-myenteric plexusMore data for this Ligand-Target Pair
Affinity DataEC50: 7.30E+3nMAssay Description:Effective concentration was measured towards mu opioid receptor using guinea pig ileum (GPI,mu) bioassay in vitroMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibitory potency against Opioid receptor mu 1 was determined in electrically induced strips of guinea pig ileum (GPI)More data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of binding of radioligand [3H]CTOP to Opioid receptor mu 1 in rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 609nMAssay Description:Binding affinity was measured against Opioid receptor mu 1 using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
Affinity DataIC50: 7.30E+3nMAssay Description:Agonist activity was evaluated in guinea pig ileum (GPI) preparations at Opioid receptor mu 1More data for this Ligand-Target Pair
Affinity DataIC50: 620nMAssay Description:Binding affinity towards mu opioid receptor was determined in rat brain using [3H]CTOP as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibitory concentration against electrically evoked contractions of guinea pig ileum longitudinal muscle-myenteric plexusMore data for this Ligand-Target Pair
Affinity DataIC50: 7.30E+3nMAssay Description:Ability to inhibit electrically evoked contractions of isolated muscle preparations of guinea pig ileum (GPI, mu receptor)More data for this Ligand-Target Pair
Affinity DataIC50: 2.72E+3nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Stimulation of [35S]GTP-gamma-S, binding to recombinant human Opioid receptor mu 1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.16E+4nMAssay Description:Inhibitory concentration for inhibition of Opioid receptor mu 1 induced contractions in guinea pig ileum (GPI) smooth muscle assaysMore data for this Ligand-Target Pair
Affinity DataIC50: 610nMAssay Description:Binding affinity towards Opioid receptor mu 1 using [3H]- CTOP as radioligandMore data for this Ligand-Target Pair
Affinity DataEC50: 7.30E+3nMAssay Description:In vitro bioassay data to determine the effective concentration required for antagonistic activity against Opioid receptor mu 1 in functional assay,G...More data for this Ligand-Target Pair
Affinity DataIC50: 2.72E+3nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
Affinity DataIC50: >3.50E+4nMAssay Description:Evaluation for the binding affinity by competitive inhibition of [3H]- CTOP bindingMore data for this Ligand-Target Pair